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​OBJECTIVE: ​​To perform long-term histopathological and clinical assessment of patients who have previously undergone cardiomyotomy for achalasia. BACKGROUND: There are few studies on long-term outcome for patients treated by cardiomyotomy for achalasia. Recent publications suggest that these patients may be at high risk of both squamous cell carcinoma and adenocarcinoma of the esophagus. METHODS: All […]

Consultant General Surgeon, Mr James Gossage, recently performed a Laparoscopic Bilateral Inguinal Hernia Repair procedure on one of his patients, a 54-year-old male.

In a European analysis reported in the Journal of Clinical Oncology, Davies et al found that pathologic tumor downstaging after neoadjuvant chemotherapy was the strongest independent predictor of overall survival in patients undergoing surgery for esophageal and esophagogastric junction adenocarcinoma. Compared with no response, downstaging was also associated with significantly lower rates of local and […]

NEW YORK (Reuters Health) – Tumor stage after neoadjuvant chemotherapy is more important than the initial tumor stage in gauging prognosis after surgery for adenocarcinoma of the esophagus and esophagogastric junction, according to a study from the United Kingdom. “This study indicates that the established local downstaging effect of neoadjuvant chemotherapy in resectable esophageal adenocarcinoma […]

Among patients with resectable esophageal adenocarcinoma, tumor stage after completion of neoadjuvant chemotherapy is a much more important predictor of survival than is initial tumor stage at…

“No previous study has been able to quantify the local and systemic downstaging effects of systemic therapy in this manner and combine it with robust long-term follow-up data,” they noted. This study was supported by the Swedish Research Council, the Swedish Cancer Society, and the National Institute of Health Research, Royal Marsden /Institute of Cancer […]

Among patients with resectable esophageal adenocarcinoma, tumor stage after completion of neoadjuvant chemotherapy is a much more important predictor of survival than is initial tumor stage at presentation, according to a report published online July 28 in Journal of Clinical Oncology. Researchers analyzed data regarding 584 consecutive resections for adenocarcinoma of the esophagus or esophagogastric […]